Category: Dr Zam’s Institute of Holistic Living

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Unraveling Insulin Resistance: A Comprehensive, Evidence-Based Exploration

Unraveling Insulin Resistance: A Comprehensive, Evidence-Based Exploration - Dr Zam's Institute of Holistic Living, Living Better Through Research

Introduction

Insulin resistance, a key player in the pathogenesis of type 2 diabetes and metabolic syndrome, has become a global health concern. This article delves into the intricacies of insulin resistance, providing a comprehensive, evidence-based overview of its mechanisms, implications, and potential therapeutic strategies.

Understanding Insulin Resistance

Insulin, a hormone produced by the pancreas, plays a crucial role in regulating glucose metabolism. It facilitates the uptake of glucose into cells, primarily muscle and adipose tissue, for energy utilization or storage. Insulin resistance is a condition where cells fail to respond effectively to insulin, leading to impaired glucose uptake, hyperglycemia, and compensatory hyperinsulinemia.

Mechanisms of Insulin Resistance

The pathophysiology of insulin resistance is multifaceted, involving genetic, epigenetic, and environmental factors.

  1. Genetic Factors: Several genes, including TCF7L2, PPARG, and FTO, have been associated with insulin resistance, highlighting the role of genetic predisposition (1).
  2. Epigenetic Factors: Epigenetic modifications, such as DNA methylation and histone modifications, can influence gene expression and contribute to insulin resistance (2).
  3. Environmental Factors: Lifestyle factors, including poor diet, physical inactivity, and obesity, are significant contributors to insulin resistance. Chronic inflammation and oxidative stress, often associated with these factors, can impair insulin signaling pathways (3).

Implications of Insulin Resistance

Insulin resistance is not merely a precursor to type 2 diabetes; it’s also linked to a plethora of health conditions:

  1. Metabolic Syndrome: Characterized by a cluster of conditions including hypertension, hyperglycemia, abnormal cholesterol levels, and abdominal obesity, metabolic syndrome is often a consequence of insulin resistance (4).
  2. Cardiovascular Disease: Insulin resistance can lead to endothelial dysfunction, atherosclerosis, and ultimately, cardiovascular disease (5).
  3. Polycystic Ovary Syndrome (PCOS): Insulin resistance is a common feature in women with PCOS, contributing to its pathogenesis (6).
  4. Non-Alcoholic Fatty Liver Disease (NAFLD): Insulin resistance can lead to excessive accumulation of fat in the liver, resulting in NAFLD (7).

Therapeutic Strategies

Addressing insulin resistance is pivotal in preventing and managing associated conditions. Here are some evidence-based strategies:

  1. Lifestyle Modifications: Regular physical activity and a balanced diet rich in whole grains, fruits, vegetables, lean proteins, and healthy fats can improve insulin sensitivity (8).
  2. Weight Management: Weight loss, particularly in individuals with obesity, can significantly reduce insulin resistance (9).
  3. Pharmacological Interventions: Medications such as metformin, thiazolidinediones, and GLP-1 receptor agonists can improve insulin sensitivity (10).
  4. Stress Management: Chronic stress can exacerbate insulin resistance. Mindfulness-based interventions, yoga, and other stress management techniques can help (11).

Conclusion

Insulin resistance, a complex metabolic disorder, has far-reaching health implications. As we continue to unravel its complexities, it’s clear that a multifaceted approach encompassing lifestyle modifications, weight management, pharmacological interventions, and stress management is crucial in addressing this global health concern.

References

  1. McCarthy, M. I. (2010). Genomics, type 2 diabetes, and obesity. New England Journal of Medicine, 363(24), 2339-2350.
  2. Ling, C., & Rönn, T. (2019). Epigenetics in Human Obesity and Type 2 Diabetes. Cell Metabolism, 29(5), 1028-1044.
  3. Samuel, V. T., & Shulman, G. I. (2012). Mechanisms for insulin resistance: common threads and missing links. Cell, 148(5), 852-871.
  4. Alberti, K. G., Eckel, R. H., Grundy, S. M., Zimmet, P. Z., Cleeman, J. I., Donato, K. A., … & Smith, S. C. (2009). Harmonizing the metabolic syndrome: a joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity. Circulation, 120(16), 1640-1645.
  5. Bornfeldt, K. E., & Tabas, I. (2011). Insulin resistance, hyperglycemia, and atherosclerosis. Cell metabolism, 14(5), 575-585.
  6. Diamanti-Kandarakis, E., & Dunaif, A. (2012). Insulin resistance and the polycystic ovary syndrome revisited: an update on mechanisms and implications. Endocrine reviews, 33(6), 981-1030.
  7. Fabbrini, E., Sullivan, S., & Klein, S. (2010). Obesity and nonalcoholic fatty liver disease: biochemical, metabolic, and clinical implications. Hepatology, 51(2), 679-689.
  8. Colberg, S. R., Sigal, R. J., Yardley, J. E., Riddell, M. C., Dunstan, D. W., Dempsey, P. C., … & Tate, D. F. (2016). Physical activity/exercise and diabetes: a position statement of the American Diabetes Association. Diabetes care, 39(11), 2065-2079.
  9. Magkos, F., Fraterrigo, G., Yoshino, J., Luecking, C., Kirbach, K., Kelly, S. C., … & Klein, S. (2016). Effects of moderate and subsequent progressive weight loss on metabolic function and adipose tissue biology in humans with obesity. Cell metabolism, 23(4), 591-601.
  10. DeFronzo, R. A., Ferrannini, E., Groop, L., Henry, R. R., Herman, W. H., Holst, J. J., … & Alberti, K. G. (2015). Type 2 diabetes mellitus. Nature reviews Disease primers, 1(1), 1-22.
  11. Marcovecchio, M. L., & Chiarelli, F. (2012). The effects of acute and chronic stress on diabetes control. Science Signal., 5(247), pt10-pt10.
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Dr Zam’s 30-Day Self-Transformation Plan

Overview:

This 30-day self-transformation plan is designed to help you evolve in a positive and sustainable manner, grounded in evidence-based psychology and theology. By following this plan, you will nurture your mind, body, and spirit, enabling you to experience lasting positive change in your life.

Weekly Breakdown:

Week 1: Developing Self-Awareness and Acceptance
Day 1-7: Focus on cultivating self-awareness and self-acceptance to create a solid foundation for change.

Week 2: Strengthening Your Relationships
Day 8-14: Nurture and enhance your relationships with others as well as your connection with a higher power (if applicable).

Week 3: Cultivating Physical, Emotional, and Mental Well-being
Day 15-21: Work on integrating healthy habits into your daily routine and learning how to manage stress effectively.

Week 4: Building Resilience, Goal Setting, and Finding Your Purpose
Day 22-30: Learn to embrace setbacks as growth opportunities, set meaningful goals, and discover your life’s purpose.

Daily Breakdown:

Week 1: Developing Self-Awareness and Acceptance

Day 1: Set an intention and commit to the 30-day plan. Begin a daily journaling practice for self-reflection.

Day 2: Practice mindfulness meditation for 10-15 minutes, focusing on the present moment.

Day 3: Identify your strengths, values, and passions using research-backed tools like the VIA Character Strengths Survey.

Day 4: Expose yourself to different perspectives by seeking out books, documentaries, and podcasts that challenge your beliefs.

Day 5: Practice self-compassion by writing yourself a letter of kindness and support.

Day 6: Assess your internal self-talk and try to replace negative thoughts with more positive, empowering thoughts.

Day 7: Reflect on the past week’s experiences and consider the progress you’ve made in cultivating self-awareness and acceptance.

Week 2: Strengthening Your Relationships

Day 8: Write a gratitude letter to someone who has had a positive impact on your life.

Day 9: Reconnect with a friend or family member you have not talked to in a while.

Day 10: Practice active listening in conversations, giving your full attention and empathy.

Day 11: Volunteer your time or resources to help a person or cause in need.

Day 12: Explore your spiritual beliefs and consider how they relate to your interpersonal connections.

Day 13: Set boundaries by identifying areas in your life where you need to say “no” to protect your well-being and relationships.

Day 14: Reflect on the progress you’ve made in strengthening your relationships and spiritual connection.

Week 3: Cultivating Physical, Emotional, and Mental Well-being

Day 15: Begin a regular exercise routine by engaging in a physical activity you enjoy.

Day 16: Improve your diet by incorporating whole foods, fruits, and vegetables.

Day 17: Establish a consistent sleep schedule and focus on developing good sleep hygiene.

Day 18: Engage in a creative hobby or activity that brings you joy and fulfillment.

Day 19: Learn and practice stress management techniques such as deep breathing, progressive muscle relaxation, or visualization.

Day 20: Foster positive emotions by practicing daily gratitude and savoring pleasant moments.

Day 21: Reflect on your progress in cultivating physical, emotional, and mental well-being.

Week 4: Building Resilience, Goal Setting, and Finding Your Purpose

Day 22: Learn to reframe setbacks by considering alternative interpretations and potential growth opportunities.

Day 23: Identify your SMART (Specific, Measurable, Achievable, Relevant, Time-bound) goals for personal and professional development.

Day 24: Break your goals into smaller, manageable steps and create an action plan.

Day 25: Seek out opportunities for personal growth, such as taking online courses, attending workshops, or joining interest groups.

Day 26: Reflect on your life’s purpose by considering how your passions and strengths intersect with the needs of the world.

Day 27: Adopt a flexible mindset and be open to changes in your goals and purpose as you continue to grow.

Day 28: Develop a support network by connecting with like-minded individuals who share your goals and values.

Day 29: Create a personal mission statement to guide your actions and decision-making.

Day 30: Reflect on the progress you’ve made during the 30-day plan and celebrate your achievements.

Remember, self-transformation is an ongoing process. Continue to apply and adapt these practices even after you complete the 30-day plan. Stay committed to personal growth, and embrace the journey of self-discovery as you seek to improve your life and the lives of those around you.

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Finding Your Purpose and Developing a Meaningful Path: A Comprehensive Guide Based on Psychology, the Holy Quran, and Islamic Teachings

Introduction

In today’s fast-paced world, the pursuit of purpose and fulfilling life can prove elusive. As a top life coach and expert in the synergy between psychology and Islamic principles, I have successfully guided individuals in their quest to discover a profound sense of purpose. Together, we’ve harnessed the guidance found in the Holy Quran and unlocked the time-tested psychological techniques that shape lives harnessing the power of positive change. In this article, you’ll uncover strategies and teachings that will empower you to embrace your potential and propel you towards a purposeful existence.

Step 1: Reflect and Identify Your Core Values

The foundation for a fulfilling life is a strong, conscious understanding of your values. To identify your core values, engage in self-reflection and consider the principles that define you. Within the Islamic teachings, values such as humility, gratitude, patience, and generosity (the Holy Quran, 2:177) are held in high regard. Aligning yourself with these values can serve as a source of purpose and provide clarity as you navigate life’s challenges.

Step 2: Define and Set Meaningful Goals

With a clear understanding of your values, transform that knowledge into actionable objectives. Develop goals that are in harmony with your soul’s purpose, as stated in the Holy Quran, “Whoever does good, it is for his own soul; and whoever does evil, it is against it” (41:46). Setting SMART (Specific, Measurable, Achievable, Relevant, and Time-bound) goals allow you to work towards a specific outcome, fueling a sense of achievement and purpose.

Step 3: Nurture Your Spiritual Connection

Building and maintaining a deep spiritual connection will provide a solid foundation for conscious growth and lasting fulfilment. In Islam, developing a strong relationship with Allah can help provide a clear sense of purpose. Engage in practices like Salah (prayers), reading and contemplating the Holy Quran, and engaging in acts of worship to nourish your spirituality.

Step 4: Develop Emotional Intelligence and Resilience

Having a fulfilling life means cultivating the ability to cope with adversity and change. Emotional intelligence, or the ability to recognize and manage our emotions, is crucial for navigating life’s challenges. Embrace emotions as guidance and leverage Islamic teachings about patience and forbearance (2:45) to foster resilience. Practising mindfulness and meditation can also help you develop skills to gain a better understanding of your emotional responses.

Step 5: Connect and Nurture Relationships

Developing strong bonds with family, friends, and the community will foster a sense of belonging, purpose, and fulfilment. Positive relationships are deeply ingrained in Islamic teachings, as mentioned in the Holy Quran, “And do good unto your parents, and near of kin, and unto orphans, and the needy…” (2:83). Work on improving communication skills, practice empathy, and be a source of support and encouragement for others to create lasting connections.

Step 6: Give Back and Serve Others

One of the most gratifying ways to live a purposeful life is to help others. Altruism and acts of kindness are encouraged in Islamic teachings (2:267) and contribute to our sense of fulfilment. By volunteering, showing compassion, or making a positive impact in someone’s life, you experience gratitude and happiness, enriching your life in turn.

Conclusion

Discovering your purpose and living a fulfilling life is not only considered a personal endeavour but a spiritual one as well. By embodying the teachings of the Holy Quran and implementing psychology-supported techniques, you can develop a meaningful path, nurture resilience, and build strong relationships. With this guidance, you will unlock the doors to a life full of meaning, purpose, and lasting fulfilment.

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Shredded at 40: A 100-Day Science-Based Plan for Men over 40

For many men over 40, the dream of achieving a shredded physique might seem like a distant goal – but it doesn’t have to be. With the help of science-based methods and a dedicated workout plan tailored for your age group, getting in the best shape of your life is entirely possible.

This article outlines a meticulous 100-day plan designed specifically for men above 40, incorporating workouts to build muscle, lose body fat, and define your physique. However, if you’re looking for a comprehensive, step-by-step transformation plan, check out my new book:

📘 Ripped at 40: The Ultimate Guide to Getting Shredded After 40

Fit, muscular man in his 40s performing strength training in a gym, showcasing a lean, ripped physique. This image represents the results of a science-based fitness plan for men over 40, as outlined in the book Ripped at 40: The Ultimate Guide to Getting Shredded After 40 by Dr Zam.

This book provides a complete roadmap for men over 40 to build lean muscle, burn fat, and maintain peak strength—without extreme dieting or exhausting workouts. You’ll get:

✔ A structured strength and cardio training program tailored for men over 40
✔ Intermittent fasting and nutrition strategies to lose fat while retaining muscle
✔ Science-backed methods to optimize testosterone and recovery
✔ A full 12-week transformation plan to get you shredded
✔ Real-life success stories from men who achieved their best physique after 40

🔥 Available now on:
🔹 Amazon Kindle: drzam.com/rippedat40-kindle
🔹 Amazon Paperback: drzam.com/rippedat40-paperback
🔹 Google Books: drzam.com/rippedat40-googlebooks

Now, let’s dive into the 100-day plan to get you started on your journey.

Phase 1: The Foundations (Days 1-30)

1. Set Realistic Goals

Before starting, establish your desired physique and composition goals, taking into account your age, medical history, and lifestyle. Setting achievable targets will keep you motivated and committed throughout the plan.

2. Develop a Balanced Diet Plan

Optimize your nutrition for muscle growth and fat loss by prioritizing:
✔ Lean proteins
✔ Complex carbohydrates
✔ Healthy fats
✔ Antioxidant-rich fruits and vegetables

Maintain proper hydration by drinking at least 8 glasses of water daily.

3. Focus on Compound Exercises

During the first 30 days, build a strong foundation through compound exercises that engage multiple muscle groups, such as:

  • Squats
  • Deadlifts
  • Bench Presses
  • Pull-Ups

Perform three full-body workouts per week, with 3-4 sets of 8-12 reps per exercise.

Phase 2: Lean Muscle Building (Days 31-60)

1. Resistance Training

Introduce strength-focused training with an upper-lower body split, targeting each muscle group twice a week.

Upper Body Workout:

  • Bench Press
  • Bent-Over Row
  • Shoulder Press
  • Dips
  • Bicep Curl
  • Tricep Extension

Lower Body Workout:

  • Front Squat
  • Romanian Deadlift
  • Leg Press
  • Hamstring Curl
  • Calf Raise
  • Plank

2. Cardiorespiratory Fitness

Include three sessions of moderate-intensity cardiovascular exercise per week (30-45 minutes per session). Activities can include:

  • Running
  • Cycling
  • Swimming
  • Hiking

This improves heart health and enhances fat loss while preserving muscle.

Phase 3: Fat Loss and Definition (Days 61-100)

1. High-Intensity Interval Training (HIIT)

HIIT is one of the most effective ways to burn fat and preserve muscle. Incorporate it 2-3 times per week.

Example HIIT Routine:

  • Warm-up: 5 minutes of light jogging
  • Sprints: 20 seconds sprint, 40 seconds walking/jogging (repeat 8-10 times)
  • Cool down: 5 minutes of light jogging

2. Circuit Training

Twice a week, include a high-intensity circuit workout:

  • Push-ups
  • Jump squats
  • Bent-over rows
  • Mountain climbers
  • Shoulder presses
  • Bicycle crunches

Perform 45 seconds of work per exercise, followed by 15 seconds rest, repeating for 4-6 rounds.

3. Advanced Strength Exercises

To challenge your muscles further, include:

  • Hanging Leg Raises
  • Cable Flys
  • Farmer’s Walks

Your Next Steps

Consistency, proper nutrition, and the right training approach will determine your results. Stick to the plan, prioritize recovery, and fuel your body properly.

For a comprehensive approach with meal plans, workout routines, and expert guidance, grab a copy of Ripped at 40: The Ultimate Guide to Getting Shredded After 40 today.

🔹 Amazon Kindle: drzam.com/rippedat40-kindle
🔹 Amazon Paperback: drzam.com/rippedat40-paperback
🔹 Google Books: drzam.com/rippedat40-googlebooks

If you’re ready to build muscle, burn fat, and transform your body, start now. Your best years are still ahead.

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The Optimal Health Benefits of a No-Sugar Nutritional Approach

Sugar, a signature ingredient in many of our daily food products, has long been considered an integral element of our diets. Recent scientific studies, however, have discovered the vast negative impacts excessive sugar consumption has on our overall health. A growing body of evidence supports the notion that a no-sugar nutritional approach can significantly boost our physical and mental well-being. In this article, we will delve into the science behind the benefits of eliminating sugar from our diets and adopting the no-sugar nutritional approach.

The Dangers Of Refined Sugar

Refined or added sugar is typically found in various food products such as soft drinks, breakfast cereals, snacks, condiments, and desserts. This type of sugar is highly processed and lacks the nutrients and fibres present in natural sugars found in fruits. Refined sugar is known to exacerbate two of the world’s leading public health issues: obesity and Type 2 diabetes. Moreover, studies have shown correlations between excessive sugar consumption and increased risks of heart disease, liver disease, and dental cavities, among other ailments.

Benefits Of A No-Sugar Nutritional Approach

  1. Weight Management

Eliminating sugar from one’s diet can aid in weight loss and help maintain a healthy body weight. Sugar-loaded food products typically contain empty calories that rarely provide satiety, leaving individuals with excessive calorie intake. By opting for a no-sugar nutritional approach, individuals can cut down on unnecessary calorie consumption and ultimately control their weight more effectively.

  1. Stabilized Blood Sugar Levels and Decreased Diabetes Risk

Cutting out sugar can help stabilize blood sugar levels and regulate the secretion of insulin, the hormone responsible for glucose absorption. As a result, individuals who follow a no-sugar diet may experience a lower risk of developing Type 2 diabetes, a chronic condition characterized by insulin resistance and high blood sugar levels.

  1. Improved Heart Health

Several studies have shown that a high sugar intake can lead to elevated levels of low-density lipoprotein (LDL) cholesterol, commonly known as “bad” cholesterol. High LDL cholesterol levels are associated with a greater risk of developing heart disease. Adopting a no-sugar nutritional approach can decrease LDL cholesterol, consequently promoting better heart health.

  1. Enhanced Brain Function and Mental Health

A no-sugar diet can also benefit cognitive function and mental health. Refined sugar has been linked to impaired cognitive abilities such as memory and learning. Additionally, sugar has been found to worsen symptoms of depression and anxiety. By eliminating sugar from the diet, individuals can see improvements in mental clarity, memory, and overall mood.

  1. Better Dental Health

Dental cavities, caused by the breakdown of tooth enamel, can be directly tied to sugar consumption. Sugar produces harmful acids that attack the tooth surface, leading to the loss of minerals essential for healthy teeth. Adopting a no-sugar nutritional approach can help prevent tooth decay as well as gum disease, ensuring long-lasting dental health.

Conclusion

There is growing evidence of the multiple health benefits associated with a no-sugar nutritional approach. By eliminating refined sugars from our diets, we can actively improve our weight management, blood sugar levels, heart health, brain function, and dental health. Despite the challenges that come with cutting out sugar, the overall impact on our wellbeing undoubtedly makes it a worthwhile endeavor.

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Top 10 Fitness Tips For Ramadan

It is Ramadan season. It is the best time to achieve a remarkable physical reset for your body, as you go through fasting for a month. It is also the best period for holistic transformation of the body, mind and soul. Here are the top 10 fitness tips for Ramadan.

#1 Stay hydrated: Drink plenty of water before and after breaking your fast to avoid dehydration.

#2 Plan your meals: Eat balanced meals consisting of complex carbohydrates, lean protein, and healthy fats to keep your energy levels up during the day.

#3 Exercise before iftar: Work out before breaking your fast to burn off calories and increase your metabolism.

#4 Choose low-intensity workouts: Exercise at a low-intensity level such as yoga, Pilates, or light cardio to avoid exhaustion.

#5 Take a break: Rest when you need to and listen to your body’s intuitive responses.

#6 Eat slowly: Enjoy your food and chew your food properly to avoid overeating.

#7 Avoid processed food: Eat whole foods such as fruits, vegetables, lean protein, and grains to avoid bloating.

#8 Sleep well: Try to get at least 7-8 hours of sleep to ensure your body has enough time to rest and recharge.

#9 Don’t skip suhoor: Eat a nutritious meal before sunrise to boost your energy levels and prevent hunger pangs.

#10 Practice mindfulness: Be mindful of your body, thoughts, and emotions to de-stress and maintain a positive mindset throughout the day.

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Reboot Your Body with our Sugar Detox Programme

Reboot Your Body with our Sugar Detox Programme. Feel more energetic, alert and focused. You deserve the best life. Science-based living for Body, Mind and Soul. #science #detox

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What is Dr Zam’s Keto IF Nutrition™?

What is Dr Zam’s Keto IF Nutrition™? How did Dr Zam lose over 70kg of fats? Yes, 70kg of fats! Almost half of his body weight at his heaviest…

At the same time, he puts on muscles and lean mass, which keeps his metabolism up.

No worries even if you are in your 40s!

It is scientifically proven to be the most effective weight loss strategy in many studies. Look out for Dr Zam’s latest ground-breaking holistic living reference book of over 1,000 studies around the world! Science-based Living for Body, Mind and Soul

Dr Zam used to suffer from Diabetes Mellitus type II. By removing sugar totally from his nutrition, he has successfully reversed diabetes and its related medical conditions. Dr Zam believes sugar is poison! We should reduce sugar to the minimum! Especially added sugars!

In the FB Live Stream coming on Thursday, 14 July 2022, 8pm to 9pm, discover:

1. What is Keto? Macronutrients?

2. Why is ketosis important for fat loss?

3. Why fat loss, not weight loss?

4. What is IF or intermittent fasting?

5. Why IF?

6. Why Keto IF? What is N.E.A.T? Why is it important in fat loss and lean mass gain?

7. What is insulin?

8. What is insulin resistance?

9. Stop your cravings and hunger pangs, how?

10. What is Dr Zam’s Keto IF Nutrition™? Why are proteins important?

11. Let’s get started! Together with Dr Zam’s Home Easy Exercise Workout Plan™

Dr Zam will also take questions during the Live session. Just comment during the session.

Stay tuned to this FB page for the Live Stream.

Brought to you by Dr Zam’s Fitness® – The Body Achieves What the Mind Believes®

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Dr Zam has helped tens of thousands of individuals to achieve their peak performance in their desired domains of life. Dr Zam is an international award-winning, best-selling author, motivational speaker, peak performance researcher and master life coach. He believes human potential is limitless, and everyone can succeed!

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Yes I Can! The Ultimate Life Transformation Challenge 2022

This is it!

The three most powerful words that would change the lives of 10 contestants in this greatest transformation challenge taking place all over social media!

YES I CAN!

Dr Zam’s Living® proudly presents The Ultimate Life Transformation Challenge.

Contestants will go through the biggest transformation of their lives, in every aspect they can imagine; including a phenomenal body transformation to getting a powerful mindset, a peaceful soul and a boost to their career as an employee or business owner. Contestants will also fix all other issues in their lives, from money, relations, family and more! This will be based on Dr Zam’s Holistic Living framework.

Will your transformation inspire the world?

It will take place over 3 months, kicking off on 9 September 2022 (9.9), with the winner being announced on 12 December 2022 (12.12). $100,000 cash and prizes to be wonContestants will win cash and prizes at every stage of the challenge, even if they are eliminated!

The Public has great power!

The public voting will decide who will be eliminated in every round, and who will be crowned the final winner of this challenge. The public decides whose transformation is most inspiring, which makes them want to be empowered to change too!

There will be 5 rounds with 2 contestants eliminated in every round. Contestants will receive tasks they will need to carry out, and goals to achieve in every round.

Rounds

Round 1: Zero Sugar, Always Sweet (Week 1)

Rewards: Contestants will all receive Dr Zam’s #1 Amazon Hot New Release for Self-Help Books, 365 Life Lessons At 40 book, Dr Zam’s Amaze™ All Natural Sweetener and Dr Zam’s Fitness® Smart Body Composition Scale when they start this round. All contestants will also receive a weekly Limitless Life Coaching™ session with Dr Zam, an international award-winning best-selling author, motivational speaker and master life coach.

Round 2: Walk the Talk (Weeks 2 – 3)

Rewards: Contestants will all receive Dr Zam’s Fitness® Ultra-Comfort Tech Performance Socks and Dr Zam’s Fitness® Shaker Bottle. All contestants will also receive a weekly Limitless Life Coaching™ session with Dr Zam, an international award-winning best-selling author, motivational speaker and master life coach.

Round 3: I Have the Power! (Weeks 4 – 7)

Rewards: Contestants will all receive Dr Zam’s Fitness® Easy Home Strengthening Resistance Bands and Dr Zam’s Fitness® Easy Home Exercise Premium Mat. All contestants will also receive a weekly Limitless Life Coaching™ session with Dr Zam, an international award-winning best-selling author, motivational speaker and master life coach.

Round 4: Fit, Fitter, Fittest (Weeks 8 – 11)

Rewards: Contestants will all receive Dr Zam’s Keto Fatloss Nutrition™ and Dr Zam’s Living® Meditation Mat. All contestants will also receive a weekly Limitless Life Coaching™ session with Dr Zam, an international award-winning best-selling author, motivational speaker and master life coach.

Round 5: Before & Ever After (Week 12)

Rewards: Contestants will inherit all the affiliate cash earnings from all past contestants. All remaining two contestants will also receive a weekly Limitless Life Coaching™ session with Dr Zam, an international award-winning best-selling author, motivational speaker and master life coach.The Ultimate Life Transformation Challenge Winner as decided by the public will win all these cash earnings, multiplied by a factor of 10! On top of this, the winner will receive a year’s supply of Dr Zam’s Amaze™ All Natural Sweetener, Dr Zam’s Keto Fatloss Nutrition™ and Dr Zam’s Limitless Life Coaching™ Programme (with a total value of over $30,000).

*details of each round will be provided to shortlisted applicants for the auditions

Auditions are open now!

We are looking for the following contestants! The public will vote on who will be the 10 contestants for the challenge. We will shortlist these candidates for the public to choose from.

  • At least 21 years old
  • Able to commit at least 3 months from September to December 2022 for the challenge – you can still continue your day-to-day life during the challenge, just need to commit to the activities taking place (approximately 10 hours per week)
  • Familiar with social media tools and platforms (Facebook, Instagram, Tik Tok, etc), and has a suitable mobile device to record videos and take photos for tasks during the challenge
  • Able to speak, and write in the English Language
  • Want to transform your life in every aspect
  • Submit your application in the form below
Share a little information about yourself.
Provide as much details as to why you want to transform your life
Choose at least one, and as many as required.
Click or drag a file to this area to upload.
Record an audition video of yourself to convince us you should be considered by the public to choose as our 10 contestants of the challenge.
Please refer to the terms of the application here: https://drzam.com/yesican-application-terms
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Molecular Basis for The Clinical Application of the Ketogenic Diet in a Variety of Diseases Including Cancer

Plate with a keto diet food

In a recent review paper published on 13 February 2022 by Dr Mari Murakami and Dr Paola Tognini, they demonstrate that recent studies indicated the variety of physiological functions on various organs through metabolites acting as energy substrates, signalling molecules and epigenetic modifiers, on top of its pronounced shifts to the cellular metabolism due to pseudo-starvation as a result of the ketogenic diet. They highlighted the latest findings on the molecular mechanisms of such a diet and its significance to the functions in the context of epigenome and microbiome.

The authors conceded while the Ketogenic diet has potential as a promising therapeutic intervention for various disorders, it could be challenging for many patients to maintain such a diet for long periods of time. However, Dr Zam’s Living® range of food and beverages under the brands of Sugarless Me!™ by Dr Zam, Dr Zam’s Amaze™ All Natural Sweeteners, Dr Zam’s Keto IF Fatloss Nutrition™ and Indulge™ Sugarfree Ice Cream as well as Oh Fatimah!™ Sugarfree Keto Real Taste of Asia, makes it palatable for anyone to stay on the ketogenic diet as a form of a permanent lifestyle.

Molecular Mechanisms Underlying the Bioactive Properties of a Ketogenic DietDownload

Reference: Murakami, M.; Tognini, P. Molecular Mechanisms Underlying the Bioactive Properties of a Ketogenic Diet. Nutrients 2022, 14, 782. https://doi.org/10.3390/nu14040782